Cascade-catalysed nanocarrier degradation for regulating metabolism homeostasis and enhancing drug penetration on breast cancer

Abstract The abnormal structure of tumor vascular seriously hinders the delivery Argentina Cow Leather One Ear Headstall and deep penetration of drug in tumor therapy.Herein, an integrated and tumor microenvironment (TME)-responsive nanocarrier is designed, which can dilate vessle and improve the drug penetration by in situ releasing nitric oxide

read more

Development of standard indicators to assess use of electronic health record systems implemented in low-and medium-income countries.

BackgroundElectronic Health Record Systems (EHRs) are being rolled out nationally in many low- and middle-income countries (LMICs) yet assessing actual system usage remains a challenge.We employed a nominal group technique (NGT) process to systematically develop high-quality indicators for evaluating actual usage of EHRs in LMICs.MethodsAn initial

read more